X-ray imaging of a single virus in 3D

mimi3d Our paper with the title “Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser” (doi:10.1103/PhysRevLett.114.098102) has been published in the journal Physical Review Letters. The article is featured in a news item in Nature and as a viewpoint by APS Physics. For links to press releases and more articles covering our publication please go to the section Press.

Automated Classification

Our article about “Automated identification and classification of single particle serial femtosecond X-ray diffraction data” (also known as “hit-finding”) has been published in Optics Express 22, pp 2497-2510 (2014). In an experiment which produced copious amounts of data, we use both algorithms analyzing diffraction images and time-of-flight spectroscopy to find when a particle is hit by the X-ray laser.

X-ray Science: The Big Guns

There is a news feature article on X-ray free electron lasers in Nature magazine describing the powerful X-ray lasers —Nature 505, pp 605 (2014). The article gives a good historical account of the challenges faced by the XFELs and the first exciting results obtained at the LCLS in Stanford. You can download the entire PDF here. This is part of a special issue dedicated to crystallography as “Crystallography turns 100″ — Nature 505, pp 585-716 (2014).

Welcome

Featured

The Laboratory of Molecular Biophysics (LMB) at Uppsala University promotes research and discoveries at the frontiers of photon science by exploring and exploiting photon-material interactions on short time scales, at high photon frequencies, and in extremely strong photon fields. LMB produced the scientific case in imaging that assured funding for the construction of the first X-ray free-electron lasers in the US (the LCLS) and Europe (the European XFEL). We also study photosynthesis and photosynthetic carbon fixation in aquatic microorganisms, primarily from the Arctic and Antarctic Oceans.